Solution for injection with gastrokinetic antiemetic effect.
50 mL vial.
Central antiemetic. The central antiemetic mechanism of action is a dopaminergic antagonism at the level of the chemoreceptor trigger zone. Peripherally, it is gastrokinetic and increases the gastrointestinal motility up to the colon with a gastric emptying action.
Treatment of vomiting of various etiologies, reflux esophagitis, nausea and gastric motility disorders. Preparation for radiological tests of the GI tract.
100 mL of the solution contains:
Metoclopramide hydrochloride 0.5 g
Excipients q.s.
0.5 mg/kg of body weight/8 hours, equivalent to 1 mL of Pileran®/10 kg of body weight/8 hours. By continuous infusion: 1-2 mg/kg of body weight/day, equivalent to 1 mL of Pileran®/2.5 – 5 kg of body weight every/day.
Do not use in gastrointestinal episodes associated with the presence of sharp foreign bodies, mechanical obstruction or digestive perforations. Contraindicated in animals with seizures and in animals medicated with neuroleptics. Do not use in patients with hypersensitivity to the main ingredient. Do not use in early stages of pregnancy or during lactation.
In rare occasions, there are effects associated with dopamine receptor blockade, characterized by behavioral changes, restlessness, disorientation, and hallucinations. A sedative effect occurs in some cases.
Use with caution in patients with liver and renal failure and in epileptic patients.
In the administration by continuous infusion, protecting the parenteral solution where Metoclopramide is diluted from light is recommended. Use with caution in debilitated animals .
